Neurologist Principal Investigator

Full-timeOn-site
Riverside, CA · Long Beach, CA · Irvine, CA · Inglewood, CA · Los Angeles, CA · Oakland, CAvia Irvine Clinical CareersPosted Apr 15, 2025
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About this role

Irvine Clinical Research is the largest independent clinical research site network on the West Coast. With 5 research centers in California, we are leaders in the search for new treatments in neurology, psychiatry, and obesity medicine. Our largest area of research is in Alzheimer’s Disease prevention and treatment drug trials, and our doctors were the largest contributors in the world to the most recently FDA-approved medication in Alzheimer’s Disease.

Irvine Clinical Research is hiring a Neurologist who will serve as a Principal Investigator. The physician will oversee Phase 1, 2, and 3 clinical trials of some of the most promising drugs under investigation in memory disorders and other neurological conditions. This includes next-generation disease-modifying anti-amyloid therapies in the same class as donanemab and lecanemab, anti-tau agents, and novel therapies like antisense oligonucleotides (ASOs).

Our hiring needs vary per location (Inglewood, Long Beach, Oakland, Riverside), so please indicate any preferred locations in your application.

Job Duties

  • Lead study team as a Principal or Sub-Investigator, ensuring trials are conducted safely and per protocol
  • Conduct clinical intake interviews to determine medical eligibility of potential study participants
  • Educate potential participants about diseases and the benefits of clinical trial participation
  • Manage the safety of study participants; respond appropriately to adverse events in a timely manner
  • Perform cerebrospinal fluid collection (lumbar puncture) in diagnostic and therapeutic studies
  • Provide medical leadership to our team of psychologists and study coordinators

Job Requirements

  • Valid license to practice medicine in California (or license-eligible)
  • Board-certified in neurology or psychiatry
  • Experience working with older adults in a clinical or research setting
  • Clinical research experience is preferred, but not required
  • A command of professional spoken and written English
  • Hours and Compensation
  • This is a full-time employment position based in-person at one of our clinics (Riverside, Inglewood, Long Beach, or Oakland). There are no planned overnight or weekend hours.

The starting salary for this position is $300,000 per year. Higher salary is available with candidates meet one of the following criteria: (1) current/previous investigator in pharmaceutical clinical trials of Alzheimer’s Disease (2) superior skill in intrathecal administration and CSF collection in clinic.

  • The company pays for 100% of health/dental/vision individual insurance costs for eligible full-time employees. Vacation (PTO) is earned at a rate of 3 weeks per year.

Before you apply

  • 1Which parts of your CV prove experience with this kind of role?
  • 2Which recent work examples would make your application stronger for this role?
  • 3What details from the original source listing should you confirm before applying?

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